Similia similibus curantur? CLL und Catharanthus roseus
نویسندگان
چکیده
منابع مشابه
The seco-iridoid pathway from Catharanthus roseus
The (seco)iridoids and their derivatives, the monoterpenoid indole alkaloids (MIAs), form two large families of plant-derived bioactive compounds with a wide spectrum of high-value pharmacological and insect-repellent activities. Vinblastine and vincristine, MIAs used as anticancer drugs, are produced by Catharanthus roseus in extremely low levels, leading to high market prices and poor availab...
متن کامل5-Methyltryptophan resistant cells of Catharanthus roseus.
Several cell lines resistant to 5-methyltryptophan were selected from wild type cells of different Catharanthus roseus suspension cultures. The resistant cells had up to 30 times the normal levels of free tryptophan. Despite the increased pool size of tryptophan anthranilate synthetase activity of resistant cells was as sensitive to inhibition by L-tryptophan as wild type cells. The overproduct...
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Revising earlier conceptual misconstructions and delving deeper into the historical debate on the origins of homeopathy, this text returns to discussions initiated in the article "Simila Similibus Curentur: historical notes on homeopathic medicine" (1997). Research has been based on two main sources: ancient texts--Corpus Hippocraticum and works by Galen, Paracelsus, and Hahnemann--and the stud...
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Genetic recombination in eukaryotes requires the pairing of homologous chromosomes to allow precise molecular exchanges between chromosome pairs at intertwined structures called Holliday junctions, the formation of which requires the action of the RecA protein. The mechanism behind the precise pairing of structures as long as chromosomes remains mysterious. In yeast, during the initial phases o...
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A procedure for cryogenic storage of alkaloid producing cell lines of periwinkle, Catharanthus roseus (L.) G. Don., has been developed. The procedure differs from established cryopreservation protocols in several aspects. Specifically, 4-day-old suspension subcultures of three cell lines were precultured in nutrient media supplemented with 1 molar sorbitol for 6 to 20 hours. The cells were then...
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ژورنال
عنوان ژورنال: Forum Médical Suisse ‒ Swiss Medical Forum
سال: 2005
ISSN: 1661-6146,1661-6138
DOI: 10.4414/fms.2005.05483